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Main Outcome Measures: (1) Photographic assessment of progression to or
treatment for advanced AMD and (2) at least moderate visual acuity loss from
baseline (> or =15 letters). Primary analyses used repeated measures logistic
regression with a significance level of.01, unadjusted for covariates. Serum
level measurements, medical histories, and mortality rates were used for safety
monitoring.
Results: Average follow-up of the 3640 enrolled study participants, aged 55-80
years, was 6.3 years, with 2.4% lost to follow-up. Comparison with placebo
demonstrated a statistically significant odds reduction for the development of
advanced AMD with antioxidants plus zinc (odds ratio [OR], 0.72; 99% confidence
interval [CI], 0.52-0.98). The ORs for zinc alone and antioxidants alone are
0.75 (99% CI, 0.55-1.03) and 0.80 (99% CI, 0.59-1.09), respectively.
Participants with extensive small drusen, nonextensive intermediate size drusen,
or pigment abnormalities had only a 1.3% 5-year probability of progression to
advanced AMD. Odds reduction estimates increased when these 1063 participants
were excluded (antioxidants plus zinc: OR, 0.66; 99% CI, 0.47-0.91; zinc: OR,
0.71; 99% CI, 0.52-0.99; antioxidants: OR, 0.76; 99% CI, 0.55-1.05). Both zinc
and antioxidants plus zinc significantly reduced the odds of developing advanced
AMD in this higher-risk group. The only statistically significant reduction in
rates of at least moderate visual acuity loss occurred in persons assigned to
receive antioxidants plus zinc (OR, 0.73; 99% CI, 0.54-0.99). No statistically
significant serious adverse effect was associated with any of the formulations.
Conclusions: Persons older than 55 years should have dilated eye examinations to
determine their risk of developing advanced AMD. Those with extensive
intermediate size drusen, at least 1 large druse, noncentral geographic atrophy
in 1 or both eyes, or advanced AMD or vision loss due to AMD in 1 eye, and
without contraindications such as smoking, should consider taking a supplement
of antioxidants plus zinc such as that used in this study.
Publication Types:
• Clinical Trial
• Multicenter Study
• Randomized Controlled Trial
Study taken from Archives of Opthalmology, Oct. 2001, 119(10): 1417-36
Antioxidants Science Cells, as they age, lose their ability to eliminate the
waste that accumulates inside; they no longer repair internal damage as well as
they used to and the cell is a very sophisticated chemical and physical machine.
Like any other machine it wears down and like any "engine" that produces energy
it produces waste.
Your cells burn glucose and oxygen as a fuel and create a toxic waste or exhaust
just like an automobile engine does burning gasoline and oxygen. The waste, or
free radicals damage the engine of the cell as well as the cell nucleus,
organelles (other manufacturing areas in the cell) and any other part of the
cell they come into contact with.
Most products that are labeled antioxidants are indeed that but they generally
do only part of the job. If you take vitamin E or vitamin C they will scavenge
for and find the free radicals inside your body. They will collect the rogue
electron but in so doing they will have added an extra electron to their own
molecular structure and an extra electron needs to be denoted to prevent it from
flying off on its own, creating a new free radical.
When SomaLife Super X enters your body, it finds its way to the cells and works
in concert with SomaVit Plus to hand off those spare electrons that are creating
havoc and clear them from the cell. The cell can function optimally and the
ticking of your biological clock is slowed giving you back youthful energy and
appearance.
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